SALTERS ADVANCED CHEMISTRY
"CHECK YOUR NOTES" : WHAT'S IN A MEDICINE?
Print the list below and tick the box supplied when you have covered the topic in your notes. Most of the points are covered in the Chemical Ideas, with supporting information in the Storyline or Activities. However, if the main source of information is the Storyline or an Activity, this is indicated.
 
1 Be able to recognise members of the following homologous series: phenols, acyl chlorides and esters.
2 The use of systematic nomenclature to name carboxylic acids and esters.
3
The acidic nature of carboxylic acids.
4
The reaction of alcohols with carboxylic acids to form esters.
5 The characteristic properties of phenols, including acidic nature, test with iron(III) chloride solution, reaction with acyl chlorides to form esters.
6 The increasing relative strengths as acids of alcohols, phenols and carboxylic acids.
7 The technique of heating under reflux for reactions involving volatile liquids (Activities WM2 and WM5.1).
8 The technique of thin-layer chromatography (t.l.c.) and the interpretation of the results (Activity WM2).
9 How the following forms of spectroscopy can be used for the elucidation of molecular structure: mass spectroscopy (m.s.) and infrared spectroscopy (i.r.)
10 The interpretation of mass spectra (molecular ion and significance of the fragmentation) for salicylic acid and simple compounds containing a limited range of functional groups (hydroxyl, carbonyl, carboxylic acid and ester groups).
11 The interpretation of infrared spectra for salicylic acid and simple compounds containing a limited range of functional groups (hydroxyl, carbonyl, carboxylic acid and ester groups). 
12 How more effective medicines can be obtained by modifying the structure of existing medicines (Storyline WM5).
13 The procedures used in developing and establishing the safety of a medicine (Storyline WM8 and Activity WM8).