| 1 |
The chemical principles behind methods which can be used
to detect ethanol in the body (g.l.c. and i.r. spectroscopy) (Storyline
MD1; Activity MD1.2). |
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| 2 |
The following reactions involving aldehydes and ketones: formation by
oxidation of alcohols, oxidation to carboxylic acids, reduction to
alcohols and reaction with hydrogen. |
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| 3 |
The mechanism of the nucleophilic addition reaction between an
aldehyde or a ketone and hydrogen cyanide. |
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| 4 |
The meaning of the terms: drug, medicine, molecular recognition,
pharmacological activity, pharmacophore, receptor site, agonist,
antagonist, lead compound (Storyline in general). |
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| 5 |
The structure of a pharmacologically active material in terms of its
functional components: pharmacore and groups which modify the pharmacore
(Storyline MD3). |
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| 6 |
The action of biologically active chemicals and how this relates to
their interaction with receptor sites. |
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| 7 |
The factors affecting the way that species interact in three
dimensions: size, shape, bond formation and orientation (Storyline
MD4). |
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| 8 |
The role of chemists in designing and making new compounds for use as
pharmaceuticals (Storyline MD3, MD4 and MD5). |
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| 9 |
The role of computer modelling techniques in the design of medicines (Storyline
MD4). |
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| 10 |
The identification of functional groups within a polyfunctional
molecule as a way of making predictions about its properties. |
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| 11 |
How to devise synthetic routes for preparing organic compounds. |
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| 12 |
The use of the following terms to classify organic reactions: hydrolysis,
oxidation, reduction, condensation and elimination. |
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| 13 |
The classification of organic reactions according to their reaction
mechanisms: nucleophilic substitution, electrophilic addition,
electrophilic substitution, nucleophilic addition and radical. |
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| 14 |
The use of a combination of spectroscopic techniques (m.s., i.r.,
n.m.r. and u.v. and visible) to elucidate the structure of organic
molecules. |
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